Eye Health – Studies on Astaxanthin
In this article we will highlight how Astaxanthin can help with certain eye health problems. According to the most recent US data (CDC), 2.5% of people over 40 are either legally blind OR have low vision. Sixty percent of the entire US population has some kind of visual correction in the form of lenses, glasses or has had eye surgery. This percentage is expected to be the same in Europe meaning 265M people in the EU. Apart from visual acuity, there are several other eye health problems as Dry eye disease, Cataract, glaucoma, AMD and more.
Causes & prevention
The most common cause of eye disorders is ageing. Over time the chance of getting eye trauma simply increases and with the body being able to cope less with the consequences of this trauma, the eye will be more prone to developing the different conditions.
One of the major concerns of scientists is blue light and high UV, as this puts constant stress on the eye. Seeing how the society has changed towards one that is almost continuously online, or at least focussed on screens all day, one can predict serious amount of individuals with eye problems in the nearby future.
Prevention of eye issues caused by screen time is important and this market is already taking off with blue light filters, special glasses and supplements.
The Role of inflammation
The incidence of AMD, Cataract, DED, and many eye related problems are higher in individuals that smoke, are overweight and aging. These individuals usually have a higher inflammation status
No wonder that many studies have involved antioxidants to decrease inflammation and reactive oxygen species. In this report we give you an update about the latest studies done with Astaxanthin, a natural antioxidant made from the algae Haematococcus Pluvialis with a special focus on Drye Eye Disease & protection against blue light.
Dry Eye Disease
The unstable tear film encountered with DED gives rise to reactive oxygen species (ROS) and an inflammation cascade responsible for symptoms like itching, redness and more.
Several animal & cell-line models have been used to study this condition. In the various studies researchers showed that Astaxanthin reduces ROS & age related markers.
Huang et al (2016) did one of the few RCT’s on DED with 2mg Astaxanthin per day and a mix of other antioxidants. 70% of the patients that received the astaxanthin indicated an improvement in their conditions after 16 weeks whereas placebo did not.
Preventing damage from blue light
Intense blue light has been shown to increase ROS 20-fold in human corneal epithelial cells models. In these same model cell viability reduced with nearly 80% (Cristaldi et al, 2020). Though most research studies use high dosages of blue light to trigger effects, experiments with several cell phone types also revealed 80% increase in ROS in human fibroblasts (Austin et al, 2018).
We can conclude that blue light leads to ROS, which in turn causes of many eye health related problems.
Several clinical trials have been conducted with Screen Workers (SW) who did 6+ hours of screen work per day. In one study researchers addressed accommodation amplitude (AA), the power of an eye to create sharp images which naturally declines during age. The subjects (38-50yrs) took 5mg of Astaxanthin per day with very significant improvement in accommodation amplitude after just 4 weeks.
Natural Astaxanthin as produced by our partner Atacama Bio in Chile comes from Haematococcus Pluvialis and is Naxa Verified. At their Atacama facilities they produce algal biomass in a highly sustainable and cost effective way.
The NatAxtin® family of products contains
PureMassTM powder | Oleoresin 5 & 10% | Microencapsulated PureMass & Oleoresin | CWD Oleoresin | Vegan Soft gels | Vegan Hard Caps